
What is Chronic Kidney Disease (CKD)?
Chronic Kidney Disease refers to the gradual decline in kidney function over months or years. The kidneys, essential for filtering waste and maintaining fluid and electrolyte balance, become unable to perform their duties efficiently, leading to an accumulation of toxins in the body.
Causes of Chronic Kidney Disease
Diabetes Mellitus (leading cause)
Hypertension (High Blood Pressure)
Glomerulonephritis (inflammation of kidney filters)
Polycystic Kidney Disease (genetic disorder)
Recurrent Urinary Tract Infections
Obstruction in the urinary tract (stones, prostate enlargement)
Symptoms of Chronic Kidney Disease
Fatigue and weakness
Swelling of ankles, feet, or hands (edema)
Shortness of breath
Nausea and vomiting
Loss of appetite
Frequent urination, especially at night
Muscle cramps and restless legs
Itchy and dry skin
Difficulty concentrating
Pathophysiology of Chronic Kidney Disease (CKD)
1. Initial Kidney Injury
The process typically begins with a primary insult to the kidneys, such as:
Diabetes (high blood glucose causing damage to glomeruli)
Hypertension (high pressure damaging blood vessels)
Chronic infections
Autoimmune diseases (like lupus nephritis)
Obstructive uropathy (blockage of urine flow)
This initial damage triggers inflammatory and fibrotic responses.
2. Loss of Nephrons
Each kidney contains about 1 million nephrons — the functional filtration units.
In CKD:
Injury to glomeruli and tubules leads to the death (sclerosis) of nephrons.
Loss of nephrons reduces the overall glomerular filtration rate (GFR).
Remaining nephrons undergo hyperfiltration (overworking to compensate).
Hyperfiltration initially maintains near-normal GFR, but over time it stresses healthy nephrons, causing further damage.
3. Progressive Glomerulosclerosis and Tubulointerstitial Fibrosis
Glomerulosclerosis: Scarring of glomeruli due to prolonged high pressure and inflammation.
Tubulointerstitial fibrosis: Fibrosis (scar tissue formation) around the kidney tubules and interstitial spaces.
Ischemia (reduced blood flow) develops due to damage to peritubular capillaries.
These changes lead to irreversible structural damage.
4. Metabolic and Hormonal Imbalances
As CKD progresses:
Uremia: Accumulation of waste products like urea, creatinine, and toxins.
Electrolyte abnormalities:
Hyperkalemia (high potassium)
Hyperphosphatemia (high phosphorus)
Hypocalcemia (low calcium)
Acidosis: Kidneys can’t excrete hydrogen ions properly, leading to metabolic acidosis.
Anemia: Reduced production of erythropoietin (a hormone stimulating red blood cells).
These systemic imbalances worsen the patient’s symptoms and organ function.
5. Activation of Renin-Angiotensin-Aldosterone System (RAAS)
Kidneys sense decreased perfusion (blood flow) due to nephron loss.
RAAS gets activated:
Causes vasoconstriction.
Promotes salt and water retention.
Increases blood pressure.
Result: Worsening hypertension, creating a vicious cycle of further kidney damage.
6. Cardiovascular Complications
CKD heavily impacts cardiovascular health:
Left ventricular hypertrophy (LVH) due to chronic hypertension.
Atherosclerosis accelerated by dyslipidemia and chronic inflammation.
Heart failure is common.
Cardiovascular disease is the leading cause of death in CKD patients.
7. Bone and Mineral Disorders (CKD-MBD)
Decreased Vitamin D activation → Hypocalcemia → Secondary hyperparathyroidism.
Excess parathyroid hormone (PTH) causes bone resorption (renal osteodystrophy).
Soft tissue calcification can occur.
Deficiencies Commonly Seen in CKD
Iron Deficiency (leading to anemia)
Vitamin D Deficiency (causing bone disease)
Calcium Deficiency and Phosphorus Retention
Electrolyte Imbalances (like high potassium)
Protein-Energy Malnutrition in advanced stages
Mental Health and Stress in CKD Patients
Chronic illnesses like CKD profoundly affect mental health. Anxiety about dialysis, lifestyle restrictions, financial stress, and fear of mortality often lead to depression and emotional distress. Addressing mental well-being is crucial to improving outcomes and quality of life.
Investigations and Diagnosis of CKD
Blood Tests: Serum creatinine, eGFR, BUN, Electrolytes
Urine Tests: Urinalysis, Proteinuria assessment
Imaging: Ultrasound or CT scan
Kidney Biopsy: In selected cases
Other Tests: Hemoglobin, Calcium, Phosphorus levels
.
Homeopathic Remedies for Chronic Kidney Disease (CKD)
Homeopathy treats the person as a whole — not just the disease. Here are some commonly indicated remedies:
1. Apis Mellifica
Useful in early-stage kidney disease with swelling (edema), scanty urine, and sensitivity to heat.
2. Arsenicum Album
For advanced CKD cases with weakness, restlessness, and intense fear of death.
3. Terebinthina
Indicated when there is blood in the urine and a strong urinary odor.
4. Mercurius Corrosivus
Severe burning during urination with rapid kidney damage.
5. Cantharis Vesicatoria
Intense burning pain with constant urge but scanty urination.
6. Lycopodium Clavatum
Chronic, slow-developing kidney disease with bloating, digestive issues, and frequent nighttime urination.
7. Berberis Vulgaris
Kidney stones with radiating pain and urinary infections contributing to CKD.
8. Plumbum Metallicum
Late-stage CKD with muscle wasting, dark urine, and paralysis tendencies.
9. Serum Anguillae
Specific remedy for renal failure with severe fluid retention and decreased urine output.
10. Digitalis Purpurea
CKD cases complicated by heart problems like weak pulse and breathlessness.
Case Studies: Homeopathic Success in Chronic Kidney Disease
Case 1: Early-Stage CKD in a Diabetic Patient
Patient: 52-year-old male, diabetic for 10 years.
Symptoms: Fatigue, puffiness around eyes, frequent urination.
Homeopathic Approach: Started on Apis Mellifica and Lycopodium based on constitutional analysis.
Outcome: Improvement in energy, reduction in swelling, and stabilization of creatinine levels within 8 months.
Case 2: Advanced CKD with Anemia
Patient: 60-year-old female, hypertensive and anemic.
Symptoms: Breathlessness, swelling of feet, emotional distress.
Homeopathic Approach: Arsenicum Album along with supportive remedies for mental calmness.
Outcome: Improved breathing, hemoglobin levels increased with homeopathic treatment combined with dietary modifications.
Case 3: CKD Secondary to Recurrent Infections
Patient: 40-year-old male, history of recurrent urinary infections.
Symptoms: Burning urination, flank pain, fever.
Homeopathic Approach: Terebinthina followed by Berberis Vulgaris.
Outcome: Significant reduction in infections, improvement in kidney parameters, no further hospitalizations over 1 year.Homeopathy for chronic kidney disease kindly please do not self medicate
Homeopathic Management of CKD
Individualized Remedies: Chosen based on physical, mental, and emotional symptoms.
Holistic Approach: Addressing nutrition, mental health, and underlying conditions.
Regular Monitoring: Blood pressure, blood sugar, kidney function tests.Homeopathy for chronic kidney disease.kindly pease do not self medicate.
Conclusion
Chronic Kidney Disease is a silent, progressive illness that affects not just the body but the mind and spirit. Early diagnosis, healthy lifestyle choices, and complementary therapies like homeopathy can greatly improve prognosis. Homeopathy offers a natural, individualized approach to slow disease progression, manage symptoms, and enhance quality of life.Homeopathy for chronic kidney disease kindly please do not self medicate
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Es ist eventuell nicht allzu schwer zu erraten, wie ein Steroid Stack eines Bodybuilders der Golden Period ausgesehen hat.
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In der Ladephase werden mehrmals täglich Globuli und Vitalstoffe eingenommen – oft wird empfohlen, die Vitalstoffe schon zehn Tage vorher einzunehmen. Der Referenzbereich ist sehr stark alters-
und geschlechtsabhängig. Aufgrund der pulsatilen Abgabe sind die Ergebnisse
von Einzelmessungen nur eingeschränkt bewertbar.
Für die Diagnose eines substitutionsbedürftigen Wachstumshormonsmangels werden in der Regel mehrere verschiedene Exams an mehreren Tagen durchgeführt.
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Bis 1985 konnten Wachstumshormone ausschließlich aus der Hypophyse von Leichen genommen werden. Doch als man feststellte, dass Menschen,
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so wie katabole, sprich abbauende Prozesse statt.
Die Proteinsynthese sorgt hierbei für den Aufbau von Muskelzellen,
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Wer Masse nicht nur zulegen, sondern auch erhalten möchte, muss mehr gesunde Fette konsumieren.
Low-Carb Diäten sind hierzu keine gute Idee, denn Testosteron wird erst vermehrt durch eine Aufnahme von gesunden Fetten produziert.
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No matter the protocol, intermittent fasting helps control general calorie consumption while permitting your body intervals of time when it’s not digesting food. Mixing creatine use with fasting is a strong method for boosting your athletic abilities and bettering your metabolic well-being. Creatine doesn’t often break your fasting period, however its results https://neurotrauma.world/does-creatine-break-a-fast-no-but-still-dont-take differ from person to person. It’s clever to speak to a well being skilled to determine out what works for you. While analysis and professional views indicate that the timing of creatine doesn’t drastically change its benefits, it’s greatest to have it through the consuming part to keep away from affecting insulin throughout fasting. When you first begin taking creatine, it’s usually really helpful to begin with a loading dose for 5-7 days, usually about 20 grams.
Some people could experience digestive issues or stomach discomfort when taking creatine, particularly on an empty stomach. It’s essential to hearken to your physique and make adjustments as wanted. Regardless Of these concerns, there are combined opinions on whether or not taking creatine during a water fast is secure or beneficial. To shed some mild on this matter, we reached out to professionals within the area to get their insights on the matter. Download the Lila app or go to getlila.com to start out your journey.
Moreover, it is necessary to stay hydrated whereas taking creatine as it could cause dehydration if not consumed with sufficient water. Total, creatine is usually a useful supplement for those seeking to improve their bodily efficiency, nevertheless it’s essential to make use of it responsibly and underneath the steerage of a healthcare skilled. Creatine supplements are available in several forms similar to powder, capsule, or liquid.
As a certified health coach, I wrote this text based mostly on my experience, consumer observations, and scientific analysis to offer practical, evidence-based insights on creatine use. In Accordance to neuroscientist Mark Mattson, a lot of fasting’s advantages are evolutionarily conserved. The human species probably ‘grew up’ fasting; even just a few decades ago 24/7 food wasn’t as readily available as it is now. Even naturally sugar-free sweeteners can have a big enough impact on insulin to kick your body out of fat-burning mode. All three of these substances may not be conventional fasting add-ons — yet all three possess advantages which may make fasting even more efficient.
But, the very last thing you want is to undo all of your exhausting work with fasting or stop your body’s state of ketosis, autophagy, and fat burning. Sure, you should take creatine on relaxation days to maintain up elevated creatine levels. This ensures your muscular tissues remain saturated and prepared on your next workout. Read in regards to the potential side effects of creatine supplementation. Whether Or Not you’re in a loading section or sustaining, consistency is key. Creatine helps build muscle mass by enhancing protein synthesis and water retention in muscle cells.
In these instances, the primary objective of fasting is dropping fats, usually whereas gaining muscle and possibly reducing the inflammation that naturally happens after an intense exercise. As a result, supplementing with amino acids, together with glutamine is helpful and the small insulin response that will happen won’t affect the general goals of the fast. The answer depends totally on why you’re fasting and what kind of fast you’re on. If you’re on a strict water fast, with possibly unsweetened tea and coffee and a goal to stay as close to zero energy as you’ll find a way to, glutamine is off-limits.
One of the considerations when it comes to fasting is the potential caloric intake from any substance consumed. However, creatine monohydrate, the commonest form of creatine complement, is extremely low in energy. A typical serving incorporates just a few calories, which is negligible within the context of a fast. Therefore, it is unlikely that the caloric content of creatine would significantly impact the metabolic state of fasting. Creatine is a naturally occurring compound present in our our bodies, primarily in the muscle tissue and mind.
Creatine typically digests and enters the bloodstream faster when taken empty abdomen. This is perfect for people looking for quick motion, especially earlier than a exercise. Nevertheless, combining it with carbs later can enhance the power of muscle tissue to retain. Adding creatine to a carbohydrate-rich drink, like fruit juice, enhances creatine uptake into muscle tissue.
All The Time verify the labels of your supplement to make sure they don’t contain further components that could break your quick. Supplementing with creatine while fasting is secure, as creatine doesn’t spike your glucose ranges and doesn’t include any carbs, protein, or fat. Creatine is also safe to take at any time of the day—whether it is within the morning, afternoon, or evening. Creatine and Intermittent Fasting Analysis indicates that consuming pure creatine monohydrate whereas intermittent fasting is unlikely to break your fasted state.
(Weight loss medicine is a more evidence-based option for individuals with weight problems.) Nonetheless, creatine can be used to help your body composition targets. Nevertheless, human research involving wholesome [18] and T2DM adults [19] did not present increased insulin secretion both when creatine was provided alone or together with exercise coaching [19,33]. Creatine is also capable of promote muscle water retention, thereby leading to changes in cell osmolarity [34]. If you would possibly be wondering whether or not a pre-workout can break your quick, read our lately published article.
how fast does creatine break down in water
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